Hair Loss After Surgery Explained

Dr. Larry Nichter
Dr. Larry Nichter

To understand why and how hair loss following surgery can occur, it is first necessary to understand the normal hair cycle. For example, everyone is constantly shedding hair (normal can be 100 scalp hairs shed per day) and this rate changes depending on many factors including surgery. Hair bulbs, the living part of hair, have three main phases: growth phase (anagen), involution/regressing phase (catagen), and the resting/quiescent phase (telogen). For the scalp the growth phase under normal conditions is 2-8 years, involution phase 2-3 weeks, and resting phase around 3 months. During times of stress such as surgery the majority of the hair can prematurely enter the rest phase, telogen, resulting in accelerated temporary hair loss. This is called telogen effluvium.

Stress and Hair Loss

Stress is a major factor in surgery-related hair loss. During stress our bodies shunt nutrients to our heart, lungs, muscles and other vital organs. As a result, hair may be weakened and in some cases, hair follicles stop producing new hair. This is called telogen effluvium. This is the most common form of hair loss and typically seen two to three months after a major body stress, such as major surgery, chronic illness, or significant infection. Other causes such as sudden change of hormone levels, especially in women after childbirth, or stopping hormone replacement. Hair may fall out from all parts of the scalp, and noticed on your pillow, shower/tub or on a hairbrush. Scalp hair may appear thinner, but it is unusual to see large bald spots. Unfortunately, all surgery involves some stress so it is important to minimize it to the extent possible. Suggestions like setting aside time in your day to both relax and exercise (walking in particular is a great stress reliever), taking part in calming activities all help. Educate yourself about your surgery and its recovery and discuss fears and concerns about your surgery with doctor, and try to focus on the final positive outcome.

Diet and Metabolism: During healing your body metabolism increases and there are increased needs for more nutrients such as protein, iron, zinc and biotin among others. Limited amounts will be diverted to wear it is needed the most with hair not being one of these places. To reduce the effects of stress on your hair, try to eat a more nutritious diet. Extra fruit and vegetables may help especially foods rich in zinc, biotin and (especially if a menstruating female) and iron. I recommend my patients take special perioperative vitamins made for this purpose as well as Arnica Montana and Bromelain to minimize inflammation.

Hormonal Changes and Hair Loss

Disruption to your normal hormonal cycle can result in hair loss. Though more pronounced in women but it can also affect men. Prolonged period of bed rest after surgery can affect this cycle, as can some of the drugs you may be given to help you heal after your operation. Limited exercise, such as walking frequently, is beneficial. Your doctor can let you know your limitations regarding exercise. It also helps to get back to eating in as regular a pattern as possible in the days after the surgery is complete.

Anesthesia and Hair Loss

It is inconclusive whether anesthesia causes hair loss, though both patients and many doctors believe there may be a link. If so, it is more likely with lengthy anesthetics periods lasting several hours rather than following shorter operations.

Limited research suggests that because anesthesia can slow down cell division, those cells which rely on fast cell division, such as hair follicles, are pushed into their resting phase. The good news is that this is temporary and the hair follicles will soon switch back to their normal irregular hair growth pattern. A large variety of things are associated with hair loss, including several diseases and hundreds of different drugs.

Field of surgery: Change of blood flow, and scarring (deep and at the skin level) can cause hair follicles to shut down restricting new hair growth. The current hair may go in the dormant phase (telogen) and fall out (telogen effluvium). Areas involved with scarring may result in areas of permanent loss of hair.

Medications: Literally hundreds of drugs may affect the growth of hair including some of which are necessary for surgical procedures. These can be direct effects or indirect effects (e.g. allergic reaction to a medication). Once the offending medication is stopped hair growth should slowly return to normal.

Other Factors: Other factors such as infection (bacterial, viral or fungal), scratching or too much pressure can result in hair loss after surgery (Positional Alopecia). All surgery represents an increased risk of infection. Once identified it needs to be treated quickly as can cause sudden hair loss. Positional Alopecia is uncommon, but can occur when the head is kept in one position for a prolonged time interval. This limits blood supply to the skin and hair follicles. Fortunately, when you sleep, you naturally move your head at intervals. This does not occur with surgeries that do not require or purposely restrict head movement. Typically this would apply to very lengthy surgeries lasting more than 6 hours.

The good news is that post-surgical hair loss doesn’t happen to most patients and, when it does, for most it comes back to normal within months.

Exparel: Loger-lasting Local Anesthetic

Dr. Nichter is pleased to announce that the long-lasting local anesthetic Exparel® will soon be available to his patients at the Pacific Center for Plastic Surgery.

Essentially Exparel is a very long-acting local anesthetic that has just been released. It lasts approximately 3 or more days following injection. This is the same length of time that a pain pump lasts and will therefore take the place of a pain pump. This means patients can enjoy the same effect of a pain pump, but without any catheters and no pain pump to carry around.

Exparel will be available for those concerned about minimizing discomfort after surgeries such as tummy tuck and breast augmentation.

Exparel costs the same as a pain pump and produces the same result but with less hassle.

From Exparel’s fact sheet:

To help control your pain after surgery, your surgeon injected EXPAREL into your surgical incision just before the end of the procedure.

  • EXPAREL is a local analgesic that contains the local anesthetic bupivacaine. Local anesthetics provide pain relief by numbing the tissue around the surgical site.
  • EXPAREL is specifically designed to release pain medication over time and can control pain for up to 72 hours.
  • In addition to EXPAREL, your surgeon may provide other pain medications to control your pain.
  • Each patient is different and responds differently to pain medication. Depending on how you respond to EXPAREL, you may require less additional pain medication during your recovery.

[…]

When your pain is under control, your body can better focus on healing. This is not the time to test your pain tolerance, or grin and bear it.Work with your surgeon and nurse to make your recovery as speedy and pain-free as possible.

  • Follow the post-op orders your nurse gave you.
  • Eat a healthy diet and drink plenty of water. Surgery stresses your body; your body responds by needing more energy to heal

Image Source: Exparel Efficacy Page

Bromelain: a pineapple extract may improve post-surgery healing

Many of my patients ask about supplements that can speed the healing process. One such supplement that I feel is efficacious, decreases bruising and speeds healing is Bromelain. Below is a summary that details some of its potential beneficial qualities.

Pineapple plant. Image: Wikimedia Commons

Bromelain is a type of enzyme found in high concentrations in pineapple plants (and other plants of the plant family Bomeliaceae). Animal studies and anecdotal evidence of the medicinal properties of this pineapple plant extract have brought to light its therapeutic value. Bromelain has also been shown to have low toxicity and produces little to no undesirable side effects.

Evidence from decades of research suggests that bromelain is effective at:

  • reducing pain
  • reducing edema
  • reducing inflammation
  • improving the potency of antibiotics.

All of these properties are related to important aspects of post-operative healing.

The FDA in the United States recognizes bromelain as generally safe, and has categorized it as a food additive. It is commercially available in capsule, tablet, powder, and liquid forms for oral consumption. The recommended dosage varies between 500 to 1,500 milligrams per day.

Evidence from early studies indicate that bromelain may be an effective pain reducer. Healthy adults showed a dose-dependent response to the extract, which reduced acute knee pain and appeared to promote their general well-being. Bromelain reduced pain when applied directly to open blisters in another study.

Bromelain may reduce healing time for soft-tissue wounds. Patients in one controlled clinical trial who took Bromelain had bruising and faster reduction of edema than patients who did not. Analysis of the results, however, showed that the effect fell short of statistical significance. Results from another study showed that patients who took vitamin supplements containing Bromelain had shortened wound-healing time than those who did not.

Bromelain enhances the action of antibiotics. An early study suggested that Bromelain makes tissues more permeable to antibiotics but the results were not statistically significant. Another study, in children, found that Bromelain significantly reduced healing time for sepsis by potentiating the antibiotics.

Studies of Bromelain’s toxicity have found it to be very low. Some reports of “gastrointestinal problems, headache, tiredness, dry mouth, skin rash, and unspecified allergic reactions” have been cited as possible side effects of high doses of Bromelain. Then again, some of these symptoms are seen with placebos. Higher doses have been correlated with stronger side effects. Overall, there have been few reports of adverse effects.

Dr. Larry Nichter

More controlled clinical trials will have to return statistically significant results before Bromelain is accepted for therapeutic purposes. The extent of its efficacy and the mechanisms by which it works must be better understood. However, because of its potential, bromelain has caught the attention of the medical community and will be the object of future research.

I hope you have found this helpful and now understand why I recommend Bromelain to my patients.

—Larry S. Nichter, MD

Citations:

  • Orsini, Roger A. “Safety & Efficacy Report: Bromelain.” Plastic and Reconstructive Surgery 118.71 Dec. (2006): 1640-44. Print.